However may be either a conjunctive adverb (signaling a contrast between ideas) or a simple adverb. When it is a conjunctive adverb placed between two independent clauses, it is preceded by a semicolon and followed by a comma. When it appears later in a clause, it is preceded and followed by commas.

I'd like to go with you; however, my schedule is just too full, [placed between independent clauses]

I'd like to go with you; my schedule, however, is just too full, [appears later in second clause]

When however is a simple adverb, it is not set off with punctuation.

However much I'd like to go, I simply do not have the time, [simple adverb modifying much]

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