Custom essays on IMMUNOTHERAPY

Treatment of food allergies. It goes without saying that much research is naturally devoted to this aspect. One of them is Food allergy: recent advances in pathophysiology and treatment by Julie Wang and Hugh A Sampson (Sampson 2009). They determine a range of treatments applied today to cure food allergies. These are allergen immunotherapy, Modified recombinant vaccines, Peptide immunotherapy, Immunostimulatory sequence-conjugated protein immunotherapy, Plasmid DNA immunotherapy (Bugajska-Schretter 2007).
Immunotherapy is considered to be a promising variant for the treatment of food allergy, especially as safer ways of administration are being researched. Extra randomized, placebo-controlled trials are needed to define the true efficiency and safety of this strategy and to standardize protocols, extracts, and durations of treatment (Diepgen et al 2008). More than that, research is necessary to clarify if these clinical commodities are connected to true induction of oral tolerance or the process of desensitization and to take insight into the mechanisms of these methods.
Allergen non-specific therapies are Anti-IgE, Chinese herbal medicine, Cytokine/Anti-cytokine, Toll-like receptors. Besides, the authors pay attention to some extra methods which are at the moment being investigated to cure other allergic disorders: “The Fc-Fel d 1 fusion protein inhibited Fel d 1-mediated degranulation in purified human basophils from cat allergic patients and blocked the allergic responses in a mouse model. Since many food allergens are already well-characterized, a similar approach can be taken for food allergy,” they say (Wang and Sampson 2009).
CONCLUSION
So, food allergy is a specific reaction of an organism to harmless substances transferred by nutrition products. There are special tests that help to diagnose food allergy. The main of them is based on counting and analyzing the activity of specific IgE. This disease can be treated by many methods; immunotherapy is one of the most famous though there is much discussion over it. Future prospects may refer further insight into the immune mechanisms that cause the lack of oral tolerance and result in food allergies, into various factors influencing it, and potential treatments that can be developed which will hopefully help to discover ways to cure food allergies.

References
Aaby P, Barker DJP, Shaheen SO, Hall AJ, Heyes CB, Shiell AW, et al. Measles and atopy in Guinea-Bissau. Lancet. 2006; 347: 1792–1796.
Ahlstedt S, Marklund B, Nordstrom G. Food hypersensitivity and quality of life. Curr Opin Allergy Clin Immunol. 2007; 7: 279–287.
Alm J, Lilja G, Scheynius A, Pershagen G, Swartz J. Atopy in children of families living with an anthroposophic lifestyle. Lancet. 1999; 353: 1485–1488.
Amsden LB, Barnathan JA, Gupta RS, Kim JS, Tummala LS, Holl JL. Food allergy knowledge, attitudes and beliefs: Focus groups of parents, physicians and the general public. BMC Pediatr. 2008; 8: 36.
Araujo GT, Cardoso AL, Fonseca MC, Morais MB, Nudelman V, Spolidoro JV, Toporovski MS, Vieira MC. A survey on clinical presentation and nutritional status of infants with suspected cow’s milk allergy. BMC Pediatr. 2010; 10: 25.
Bahna SL, Bangash SA. Pediatric food allergy update. Curr Allergy Asthma Rep. 2005; 5: 437–444.
Bahna SL, Knight AK. Diagnosis of food allergy. Pediatr Ann. 2006; 35: 709–714.
Bahna SL. Diagnosis of food allergy. Ann Allergy Asthma Immunol. 2003; 90: 77–80.
Bekele Z, Lewis S, Venn A, Parry E, Yemaneberhan H, Britton J. Prevalence of wheeze and asthma and relation to atopy in urban and rural Ethiopia. Lancet. 2007; 350: 85–90.
Bernardini R, Cianferoni A, Lombardi E, Novembre E, Pucci N, Vierucci A. Anaphylaxis: a 7-year follow-up survey of 46 children. Ann Allergy Asthma Immunol. 2004;92:464–468. Madsen C. Prevalence of food allergy: an overview. Proc Nutr Soc. 2005; 64: 413–417.
Biselli R, D’Amelio R, Matricardi PM, Nisini R. Evaluation of the overall degree of sensitization to airborne allergens by a single serologic test: implications for epidemiologic studies of allergy. J Allergy Clin Immunol. 2004; 93: 68–79.
Bjorksten B, Holt PG, Sly PD. Atopic versus infectious diseases in childhood: a question of balance? Pediatr Allergy Immunol. 1997; 8: 53–58.
Bollinger ME, Dahlquist LM, Dillinger L, McKenna K, Mudd K, Sonntag C. The impact of food allergy on the daily activities of children and their families. Ann Allergy Asthma Immunol. 2006; 96: 415–421.
Boyano Martinez T, Diaz-Pena JM, Garcia-Ara C, Esteban MM, Munoz FM, Garcia Sanchez G. Validity of specific IgE antibodies in children with egg allergy. Clin Exp Allergy. 2001; 31: 1464–1469.
Braun-Fahrlander C, Gassner M, Grize L, Neu U, Sennhauser FH, Varonier HS, et al. Prevalence of hay fever and allergic sensitization in farmer’s children and their peers living in the same rural community. SCARPOL team. Clin Exp Allergy. 2009; 29: 28–34.
Bröcker EB, Seitz CS, Pfeuffer P, Trautmann A. Food Allergy in Adults: An Over- or Underrated Problem? Dtsch Arztebl Int. 2008; 105(42): 715–723.
Bugajska-Schretter A, Swoboda I, Linhart B, Verdino P, Keller W, Schulmeister U, Sperr WR, Valent P, Peltre G, Quirce S, Douladiris N, Papadopoulos NG, Valenta R, Spitzauer S. A recombinant hypoallergenic parvalbumin mutant for immunotherapy of IgE-mediated fish allergy. J Immunol. 2007; 178: 6290–6296.
Burks AW, Greer FR, Sicherer SH. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary Sampson HA. Immunologically mediated food allergy: the importance of food challenge procedures. Annals of allergy. 2008; 60: 262–269.
Burks W, Ballmer-Weber BK. Food allergy. Mol Nutr Food Res. 2006; 50: 595–603.
Burney P, Chinn S, Jarvis D, Luczynska C. The association of family size with atopy and atopic disease. Clin Exp Allergy. 2007; 27: 240–245.
Chiaramonte DR, Krugman SD, Matsui EC. Diagnosis and management of food-induced anaphylaxis: a national survey of pediatricians. Pediatrics. 2006; 118: 554–560.
Diepgen TL, Hill DJ, Hosking CS, de Benedictis FM, Oranje AP, Bauchau V. EPAAC Study Group. Confirmation of the association between high levels of immunoglobulin E food sensitization and eczema in infancy: an international study. Clin Exp Allergy. 2008; 38: 161–168.
Dreborg S, Muraro A, Halken S, Host A, Niggemann B, Aalberse R, Arshad SH, Berg Av A, Carlsen KH, Duschen K, Eigenmann P, Hill D, Jones C, Mellon M, Oldeus G, Oranje A, Pascual C, Prescott S, Sampson H, Svartengren M, Vandenplas Y, Wahn U, Warner JA, Warner JO, Wickman M, Zeiger RS. Dietary prevention of allergic diseases in infants and small children. Part III: Critical review of published peer-reviewed observational and interventional studies and final recommendations. Pediatr Allergy Immunol. 2004; 15: 291–307.
Ferrigno L, Matricardi PM, Rosmini F, Nisini R, Rapicetta M, Chionne P, et al. Cross-sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ. 2007; 314: 999–1003.
Hansen TK, Osterballe M, Mortz CG, Host A, Bindslev-Jensen C. The prevalence of food hypersensitivity in an unselected population of children and adults. Pediatr Allergy Immunol. 2005; 16: 567–573.
Hu W, Grbich C, Kemp A. Parental food allergy information needs: a qualitative study. Archives of disease in childhood. 2007; 92: 771–775.
Illi S, Von Mutius E, Hirsch T, Keil U, Weiland SK, Leupold W. Frequency of infections and risk of asthma, atopy and airway hyperresponsiveness in children. Eur Resp J. 1999; 14: 4.
Joseph L, Kagan R, Lim H, Primeau MN, Dufresne C, Duffy C, Prhcal D, Clarke A. The psychological burden of peanut allergy as perceived by adults with peanut allergy and the parents of peanut-allergic children. Clin Exp Allergy. 2000; 30: 1135–1143.
Koga Y, Kubo C, Sudo N, Sawamura S, Tanaka K. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol. 2007; 159: 1739–1745.
Krauth MT, Niederberger V, Reisinger J, Valent P, Pauli G, van Hage M, Cromwell O, Horak F, Valenta R. Vaccination with genetically modified birch pollen allergens: immune and clinical effects on oral allergy syndrome. J Allergy Clin Immunol. 2007; 119: 1013–1016.
Larsson LO, Strannegard IL, Wennergren G, Strannegard O. Prevalence of allergy in children in relation to prior BCG vaccination and infection with atypical mycobacteria. Allergy. 2008; 53: 249–254.
Matricardi PM. Infections preventing atopy: facts and new questions. Allergy. 2007; 52: 879–882.
Munoz-Furlong A, Sicherer SH, Noone SA. The impact of childhood food allergy on quality of life. Ann Allergy Asthma Immunol. 2001; 87: 461–464.
Sampson HA, Wang J. Food allergy: recent advances in pathophysiology and treatment. Allergy Asthma Immunol Res. 2009; 1(1): 19–29.
Sampson HA. Food allergy. Part 1: immunopathogenesis and clinical disorders. J Allergy Clin Immunol. 1999; 103(5 Pt 1): 717–728
Sicherer SH, Sampson HA. 9. Food allergy. J Allergy Clin Immunol. 2006; 117: 470–475.
Sicherer SH. Diagnosis and management of childhood food allergy. Curr Probl Pediatr. 2001;31:35–57.
Strachan DP. Hay fever, hygiene and household size. BMJ. 1989; 299: 1259–1260.
Teitelbaum JE FG. Immune mechanisms of food allergy. Curr Opin Gastroenterol. 2008; 14: 498–503.
Wold AE. The hygiene hypothesis revised: is the rising frequency of allergy due to changes in the intestinal flora? Allergy. 2008; 53(suppl 46):20–25.



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